Thomas the Rhymer 
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RE: HPV Vaccine Makes Girls ‘Retarded’
Bump. I just read a fascinating article on how the HPV vaccine may be linked to chronic fatigue syndrome and chronic pain syndrome.
source:
http://www.medscape.com/viewarticle/854469
I myself previously stated in another thread my reservations regarding the HPV vaccine, so this kind of represents my nightmares coming true -
/thread-34230...#pid681559
I'm not sure if you guys will be able to follow the link so what follows is a cut and paste of the highlights of the article:
Medscape Wrote:Chronic Symptoms After HPV Vaccination: Danes Start Study
Zosia Chustecka
November 13, 2015
The controversies surrounding the human papillomavirus (HPV) vaccination and a possible association with chronic symptoms in girls and young women appear to be ongoing, despite a recent major review that dismissed the link.
Last week, the European Medicines Agency (EMA) announced that a task force found no causality between the vaccination and two sets of chronic symptom syndromes in girls and young women, which echoes previous reassurances from the Centers for Disease Control and Prevention (CDC).
Now, some clinicians and scientists say the EMA report is "not valid" and is marred by conflict of interest and reliance on already published data and are calling for an independent study of the association.
Perhaps even more notably, Denmark has announced that it is conducting its own independent investigation. More than 1300 girls and young women with such symptoms have been referred to five specialist centers in the country.
It was Denmark that requested the recent review by the EMA into the safety of HPV vaccines. That review, which began in July, focused in particular at reports of complex regional pain syndrome (CRPS), a chronic pain condition affecting the limbs, and postural orthostatic tachycardia syndrome (POTS), a condition in which the heart rate increases abnormally after sitting or standing up, causing symptoms such as dizziness and fainting, as well as headache, chest pain, and weakness.
As reported last week, the EMA review found that "evidence does not support that vaccines cause CRPS or POTS."
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But the findings of this review are being questioned by specialists who have been treating girls with symptoms after HPV vaccination.
One of these is Jesper Mehlsen, MD, director of research at the Coordinating Research Centre/Syncope Unit at Frederiksberg Hospital, Denmark. This Syncope Unit has seen approximatley 250 young women and girls with symptoms that began less than 2 months after vaccination, he says.
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The researchers describe a "collection of symptoms consistent with pronounced autonomic dysfunction coupled with severe nonmigraine-like headache, excessive fatigue, cognitive dysfunction, gastrointestinal discomfort, and widespread pain of a neuropathic character."
"We suspect a connection to the HPV vaccine due to the close temporal association and the lack of alternative explanations," Dr Mehlsen told Medscape Medical News.
Asked for a reaction to the EMA review findings, Dr Mehlsen said: "Unfortunately the decision is based on register studies with a focus on POTS and CRPS. These diagnostic entities are only part of the symptom complex, which bear a closer relationship to chronic fatigue syndrome. In some countries, POTS is not registered as a diagnosis and patients are classified under different diagnoses in different countries. Finally, a lot of the reporting stems from the producers of the vaccines, allowing for possible heavy bias in the data."
"I would therefore strongly question the validity of the derived conclusion," Dr Mehlsen told Medscape Medical News.
A similar reaction comes from another specialist who has been treating girls with chronic symptoms after HPV vaccination, this time in the Unites States.
Svetlana Blitshteyn, MD, clinical assistant professor of neurology at the University at Buffalo School of Medicine in New York, runs a dysautonomia clinic in Getzville, New York. She has documented six cases of POTS after HPV vaccination (Eur J Neurol. 2014;21:135-139), and has since seen about a dozen more. These patients present with POTS, small fiber neuropathy, fibromyalgia, chronic daily headache, and other disorders that began shortly after HPV vaccination, Dr Blitshteyn recently told Medscape Medical News.
"Most of these young women were healthy prior to vaccination, and many were competitive athletes. After developing postvaccination syndrome, these patients became very ill, experienced significant decline in functioning, and were unable to attend school, participate in their previous athletic activities, or maintain their grades," she added.
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"Those of us who are involved in the care of patients who developed post-HPV vaccine syndrome know that for these girls, getting HPV vaccine has not been life-saving, as the pharmaceutical industry and medical professionals have been claiming, but has been life-changing in the sense that these previously healthy girls became severely ill and disabled within days to weeks after vaccination," Dr Blitshteyn told Medscape Medical News.
"Additionally, there are a number of girls whose symptoms became progressively worse after each subsequent HPV vaccine injection, suggesting that there is evidence of rechallenge," she said.
The link between HPV vaccine and POTS/CRPS cannot be denied for these affected individuals, despite the conclusion of the EMA review.
"With a large number of injured patients reported from Denmark, Japan, Mexico, United States, and the United Kingdom, the link between HPV vaccine and POTS/CRPS cannot be denied for these affected individuals, despite the conclusion of the EMA review," Dr Blitshteyn commented.
The conclusions have also been questioned by an independent researcher who has not been involved with HPV vaccination or treating individuals with symptoms. Karsten Juhl Jørgensen MD, DMedSci, senior researcher at the Rigshospitalet in Copenhagen, and part of the Nordic Cochrane Group, which is well known for repeatedly questioning data for mammography screening and other practices, told Medscape Medical News that the EMA review "highlights a fundamental problem in the way we authorize and control use of medications, including vaccines."
"The framework allows that the decisive evidence is produced by industry and that those who evaluate this evidence and make official recommendations are allowed to have substantial conflicts of interest with the same companies. In this case, a further problem seems to be that those involved in the original investigations of the vaccine are involved in evaluating the same evidence in the present EMA report and make recommendations," he said.
"It is never a good solution to allow people to be their own judges; indeed, there are strict regulations against this in many other societal contexts. Current procedures do not create the trust in medications and vaccines we would like," Dr Jørgensen said.
As for how the EMA review was conducted, he says: "As I understand it, the actual background material for their recommendations is not made available to the public, which can certainly be criticized. However, it must be based on already published studies and safety reports submitted to EMA. It is not a new primary study. This means that many of the limitations to the original studies also applies to this context (e.g., the original studies did not have sufficient follow-up to monitor harms and they did not compare vaccine to placebo, but to inactive vaccine)."
"The limitations of the original studies does not allow strong conclusions about the harms of the intervention. A new thorough independent study would be necessary to re-establish trust in the vaccine," Dr Jørgensen told Medscape Medical News.
Danish Investigation
Denmark is continuing its own investigation into the issue. The Ministry of Heath has given 7 million DKK (US$1.01 million) for research to be conducted by specialists who are seeing girls with symptoms after HPV vaccination and who are independent of the pharmaceutical industry.
"In Denmark, we have five regional centers for these patients," Dr Mehlsen told Medscape Medical News. Investigations are "focusing on autoantibodies in particular against receptors in the autonomic nervous system and we are exploring the possibility of neuroinflammation, small fiber disease, and mitochondrial dysfunction as a basis for the symptoms." He hopes that there may be some results available within the first half of 2016.
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Japan also has designated specialist centers to deal specifically with individuals who develop symptoms after HPV vaccination, and has issued guidelines for healthcare professionals.
In other countries, there have been media reports of girls who have developed symptoms and have struggled to find medical help, and media reports of chronic symptoms following HPV vaccination continue to appear from countries all around the world.
Just this week, a television documentary in New Zealand detailed cases of four girls with chronic pain who had been fit and active and are now in wheelchairs, as well as two deaths
In the United Kingdom, these media reports date back to 2008, when a national program of HPV vaccination in schools was launched. Earlier this year, affected families established the UK Association of HPV Vaccine Injured Daughters (AHVID).
...
Meanwhile, health authorities continue to emphasize the safety of the HPV vaccines.
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